Get An Atlas of Parkinson's Disease and Related Disorders PDF

By Perkin G David

ISBN-10: 1850709432

ISBN-13: 9781850709435

Any dialogue of the scientific features of Parkinson's disorder needs to take into consideration the inaccuracies of scientific prognosis. In a successive sequence of a hundred sufferers with a medical analysis of Parkinson's sickness, basically seventy six fulfilled the standards for analysis at autopsy exam. makes an attempt to tighten the diagnostic standards result in elevated specificity yet with decreased sensitivity.In An Atlas of Parkinson's affliction and comparable issues Dr. David Perkin has compiled a chain of images highlighting quite a few points of Parkinson's affliction and comparable motor problems. The publication presents an invaluable pattern of scientific, investigative (CT, MRI, and puppy) and pathological photos with succinct descriptive textual content of the issues featured. nearly one-third of the fabric during this ebook is pathological, incorporating either macroscopic and microscopic sections. one other zone of the cloth is represented by means of imaging, largely magnetic resonance imaging (MRI) and positron emission tomography (PET) scanning. the realm of stream problems has been fairly fruitful for puppy scanning, which provides, with the improvement of particular ligands for some of the receptor websites, to extra extend realizing of the pathophysiological mechanisms of the circulate problems. Reflecting the top criteria medical images and imaging besides the celebrated author's professional wisdom of the topic, Dr. Perkin's An Atlas of Parkinson's sickness and similar issues is the definitive and crucial medical reference in its box.

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Download e-book for kindle: An Atlas of Parkinson's Disease and Related Disorders by Perkin G David

Any dialogue of the medical features of Parkinson's sickness needs to take into consideration the inaccuracies of medical analysis. In a successive sequence of a hundred sufferers with a scientific analysis of Parkinson's sickness, purely seventy six fulfilled the standards for prognosis at autopsy exam. makes an attempt to tighten the diagnostic standards bring about elevated specificity yet with lowered sensitivity.

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The axial proton-density MRI (lower) shows hyperintensity of the transverse pontine fibers, middle cerebellar peduncles and cerebellum in olivopontocerebellar atrophy ©2004 CRC Press LLC Figure 43 PET scans showing local cerebral metabolic rate for glucose in a normal control compared with patients with multiple system atrophy (MSA), sporadic olivopontocerebellar atrophy (sOPCA) and dominantly-inherited olivopontocerebellar atrophy (dOPCA) ©2004 CRC Press LLC Figure 44 Macroscopic view of the brain in corticobasal degeneration.

The axial proton-density MRI (lower) shows hyperintensity of the transverse pontine fibers, middle cerebellar peduncles and cerebellum in olivopontocerebellar atrophy ©2004 CRC Press LLC Figure 43 PET scans showing local cerebral metabolic rate for glucose in a normal control compared with patients with multiple system atrophy (MSA), sporadic olivopontocerebellar atrophy (sOPCA) and dominantly-inherited olivopontocerebellar atrophy (dOPCA) ©2004 CRC Press LLC Figure 44 Macroscopic view of the brain in corticobasal degeneration.

COMT, catechol O-methyltransferase; +, by stimulation; –, by inhibition ©2004 CRC Press LLC Figure 17 Dystonic posturing secondary to dopa therapy. There is hyperextension of the left big toe Figure 18 Dystonic posturing of the right thumb and little finger (on the left) secondary to dopa therapy ©2004 CRC Press LLC Figure 19 CT of a patient with previous bilateral thalamotomies (arrowed) performed for control of a Parkinsonian tremor Figure 20 Fluorodopa-uptake studies in a patient following dopaminergic grafting ©2004 CRC Press LLC Figure 21 Coronal brain section showing abnormal white matter (white arrow) above the ventricular roof with relative preservation of subcortical white matter (U fibers; black arrow) Figure 22 Histology showing parietal white matter at the bottom of the cortex, a relatively preserved (but not quite normal) arcuate zone (white arrow), and rarefied pale-staining deep white matter, containing thick-walled arteriosclerotic blood vessels lying in dilated and fibrotic perivascular spaces (black arrow)(Luxol fast blue–H & E) ©2004 CRC Press LLC Figure 23 Histology showing a lacunar infarct (pale area) with an irregular cavity lined by reactive cells (astrocytes and macrophages).

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An Atlas of Parkinson's Disease and Related Disorders (Encyclopedia of Visual Medicine Series) by Perkin G David


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